Rules and Guidelines


  1. Students attending school in the United States and Canada may apply to the 2022 BioGENEius Challenges.
  2. Students must be enrolled in biology or science-related courses (Grade 9 to 12) in any public or private school and home schools.
  3. Project must have a biotechnology application. For the purposes of this program, we will use the following definition of biotechnology: "Biotechnology is the use of the knowledge of biological systems to produce goods and services."
  4. Individual Students Only, may submit ONE project for this competition.  (We will accept projects that have a group component only if the student individually completed a major component of the project. The student will be allowed to mention the group component but is not allowed to report on other students' findings.)
  5. Research presented in 2022 must be NEW research. Projects may be continued research from previous years. Any project conducted in a similar area of research as previous projects should be considered a continuation. If the project is a continuation, explain as completely as possible how the project differs from previous years and what is the significant progress. Explain when the actual experimental procedure (not the background literature review) will begin and end because ONLY a 12-month project that occurred within the last 18 months before this year’s International BioGENEius Challenges is allowed.



The International BioGENEius Challenges has adopted the Intel ISEF ethics statement which is stated below to which each student must adhere. Students found in non-compliance with these principles will be automatically disqualified.

“Scientific fraud and misconduct are not condoned at any level of research or competition. Such practices include plagiarism, forgery, use or presentation of other researcher’s work as one’s own and fabrication of data. Fraudulent projects will fail to qualify for competition in affiliated fairs or the” BioGENEius Challenge.1

1. Society for Science and the Public. "International Rules for Precollege Science Research: Guidelines for Science and Engineering Fairs." International Science and Engineering Fair Rules for All Projects. Ed. ISEF SRC. Science for Science and the Public. 29 Jan 2015



  1. A project is deemed relevant if its content relates to the various applications of biotechnology such as health care, agriculture and forestry, food processing, mining and the environment, and forensics; and it applies the knowledge and techniques of the current courses at school and/or other scientific studies such as biochemistry, molecular biology, cell biology, microbiology and biotechnology.
  2. The project must include scientific experiments that recognize and control all significant variables and demonstrate excellent collection, analysis and presentation of data.
  3. The project should not involve the use of any dangerous chemicals or biohazardous materials, except under the direct supervision of qualified personnel with appropriate permission and consent forms completed and on file. All required permissions and paperwork of the International Science and Engineering Fair must be completed in advance of conducting the project.
  4. The project should conform in general with the guidelines for International Science and Engineering Fair Guidelines (ISEF).



In recent years, students have done research on groundbreaking topics from optical tweezers to advance detection of resistant bacteria in hospitals to microbial fuel cells. With COVID restrictions, innovative research has utilized AI, convolutional neural network algorithms and other computational sciences - all done at home! Bottom line: be innovative, novel, and have current or future relevancy.